Abacavir / lamivudine / zidovudine Drug Information


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Home :: Medications :: Abacavir/lamivudine/zidovudine

Abacavir / lamivudine / zidovudine Drug Information

Generic Name: Abacavir / lamivudine / zidovudine

Brand Name: Trizivir

What is abacavir-lamivudine-zidovudine (Trizivir)?

Trizivir tablets are a combination of three medicines: abacavir (Ziagen), lamivudine (Epivir), and zidovudine (Retrovir) which each belong to a group of medicines called antiretrovirals. Abacavir / lamivudine / zidovudine (Trizivir) is used for the treatment of human immunodeficiency virus (HIV) infection. HIV causes acquired immune deficiency syndrome (AIDS).

Abacavir-lamivudine-zidovudine (Trizivir) is not a cure for HIV or AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow progress of the disease.

How to Take Abacavir / lamivudine / zidovudine:

Take this medicine as directed by the doctor. Abacavir-lamivudine-zidovudine (Trizivir) can be taken with or without food. Take each dose with a full glass of water. Do not stop taking this medicine abruptly without consulting with your doctor.

What are the Side Effects of Abacavir- lamivudine-zidovudine -

Like all medicines, TRIZIVIR tablets can cause some side-effects. Some common side effects reported with this medicine include the following. Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Extreme weakness, tiredness, or confusion
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Rapid breathing or trouble breathing, nausea and vomiting
  • Swelling in your hands, ankles, or feet
  • Unusual bleeding, bruising, or weakness
  • Yellow skin or eyes If you notice these less serious side effects, talk with your doctor:
  • Headache, dizziness, trouble sleeping
  • Mild nausea, vomiting, loss of appetite
  • Unusual weight gain or increased fat in some parts of your body.

Warnings and precautions before taking Abacavir / lamivudine / zidovudine (Trizivir):

  • Do not take abacavir-lamivudine-zidovudine (Trizivir) if you have ever had an allergic reaction to this combination medication or to abacavir (Ziagen), lamivudine (Epivir), or zidovudine (Retrovir) in the past.
  • Talk with your physician or pharmacist if you are taking other medications.
  • Abacavir, lamivudine, and zidovudine combination has not been studied in pregnant women. However, abacavir has been found to cause birth defects and other problems in animals at doses many times the human dose, and zidovudine has been studied in animals and causes birth defects when given in very high doses. Before taking this abacavir, lamivudine, and zidovudine combination, make sure your doctor knows if you are pregnant or if you may become pregnant
  • Stop taking abacavir-lamivudine-zidovudine (Trizivir) and seek emergency medical attention if you develop a fever, a skin rash, fatigue, nausea, vomiting, diarrhea, abdominal pain, severe tiredness, achiness, general ill feeling, sore throat, shortness of breath, or cough.

What to do if you take Overdose of Abacavir / lamivudine / zidovudine?

If you think you or anyone else may have taken too many TRIZIVIR tablets immediately telephone your doctor or contact your local or regional Poisons Information Centre Seek medical attention immediately. You may need urgent medical attention.

What to do if you take Missed Dose of Abacavir / lamivudine / zidovudine?

If you miss a dose of Abacavir / lamivudine / zidovudine medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

How to Store Abacavir / lamivudine / zidovudine:

Store abacavir-lamivudine-zidovudine (Trizivir) at room temperature away from moisture and heat. Keep this medicine where young children cannot reach them such as a locked cupboard.

Keep TRIZIVIR tablets in a cool, dry place where it stays below 30ºC.

Keep your TRIZIVIR tablets in their pack until it is time to take them.

If your doctor tells you to stop taking TRIZIVIR tablets, or the tablets have passed their expiry date, return any unused or expired medicine to your pharmacist.


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